What can HalioDx do for you?

What can HalioDx do for you?

Use our immune-oncology IVD solutions IMMUNOSCORE® in Localized Colon Cancer and IMMUNOSCORE® IC in Non-Small Cell Lung Cancer to improve patient care management with immune contexture information.

Immunoscore® family assays

Immunoscore® is an in vitro diagnostic test predicting the risk of relapse in early stage colon cancer patients, by measuring the host immune response at the tumor site. This test can be ordered by oncologists for their patients for a better disease management.

Immunoscore ® IC is an assay for the detection of PD-L1 protein and the concomitant detection of CD8 + cells in Non-Small Cell Lung cancer (NSCLC) tissue.

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Reousrces on IMMUNOSCORE® in Colon Cancer and on IMMUNOSCORE® IC in NSCLC



#Immunoscore® Colon
Publication

#publication | Sep. 2020

Mlecnik B Bifulco C, Bindea G, et al.

Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer

J Clin Oncol.

#Immunoscore® Colon
Publication

#publication | Aug. 2020

El Sissy C, Kirilovsky A, Van den Eynde M et al.

A Diagnostic Biopsy-Adapted Immunoscore Predicts Response to Neoadjuvant Treatment and Selects Patients with Rectal Cancer Eligible for a Watch-and-Wait Strategy

Clin Cancer Res

#Immunoscore® Colon
Publication

#publication | Aug. 2020

Bruni D, K Angell H and Galon J

The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy

Nature Reviews Cancer

#Immunoscore® Colon
Video

#video | Jul. 2020

Immunoscore® highlights at ESMO GI. Presentations of Dr Le Bagousse and Jérôme Galon, PhD
#Immunoscore® Colon
Publication

#publication | Jun. 2020

O’Connor JM, Esteso F & Chacón M

Official French SARS-CoV-2 guidelines for cancer patients, a triage solution with precision medicine

Future Medicine

#Immunoscore® Colon
Video

#video | Jun. 2020

Testimonial: Dr Juan Manuel O’Connor (Instituto Alexander Fleming in Buenos Aires, Argentina) on the use of Immunoscore in routine practice in managing early Colon Cancer
#Immunoscore® Colon
E-news

#e-news | Jun. 2020

Factsheet Immunoscore® & COVID-19 Colon Cancer Guidelines
#Immunoscore® Colon
Poster

#poster | May. 2020

Poster presented at ASCO20 Virtual Scientific meeting#ASCO20

Immunoscore is the most powerful parameter predicting time to recurrence and disease-free survival in T4N0 stage II colon cancer patients Abstract 4105

#Immunoscore® Colon
Publication

#publication | May. 2020

Marliot F, Chen X, Kirilovsky A et al.

Analytical validation of the Immunoscore and its associated prognostic value in patients with colon cancer

BMJ

#Immunoscore® Colon
E-news

#e-news | May. 2020

Expert Opinion: The Role of Microbiota and its Impact on the Tumor Microenvironment in Colorectal Cancer | Dr Benjamin A. Weinberg, MD, Oncologist in Georgetown, Washington DC
#Immunoscore® Colon
E-news

#e-news | Apr. 2020

Expert Opinion: Immunity and cancer | Dr Angela Alistar, MD, Oncologist in Morristown, NJ
#Immunoscore® Colon
Publication

#publication | Apr. 2020

Pages F, Andre T, Taieb J et al.

Prognostic and Predictive Value of the Immunoscore in Stage III Colon Cancer Patients Treated With Oxaliplatin in the Prospective IDEA France PRODIGE-GERCOR Cohort Study

Annals of Oncology

#Immunoscore® Colon
Publication

#publication | Apr. 2020

Sinicrope F, Shi Q, Hermitte F et al.

Contribution of Immunoscore and Molecular Features to Survival Prediction in Stage III Colon Cancer

JNCI Cancer Spectrum

#Immunoscore® Colon
Publication

#publication | Mar. 2020

Blair H

Immunoscore®: A Diagnostic Assay for Clinical Management of Colon Cancer

Molecular Diagnosis & Therapy volume

#Immunoscore® Colon
Video

#video | Mar. 2020

Franck Pagès, MD, PhD, on Selecting Patients With Advanced Colon Cancer for Treatment
#Immunoscore® Colon
Poster

#poster | Jan. 2020

Poster presented at Gastro Intestinal Symposium #GI20

Prognostic and predictive value of the Immunoscore in stage III colon cancer patients treated with mFOLFOX6 (3 vs 6 months) in the prospective IDEA France cohort study

#Immunoscore® Colon
Publication

#publication | Jan. 2020

Pagès F, Kirilovsky A, Mlecnik B et al.

In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer.

Journal of Clinical Oncology

#Immunoscore® Colon
Brochure

#brochure | Dec. 2019

Brochure Immunoscore® in Localized Colon Cancer

For Patients & Caregivers (English)

#Immunoscore® Colon
Brochure

#brochure | Dec. 2019

Brochure Immunoscore® in Localized Colon Cancer

For Patients & Caregivers (Spanish)

#Immunoscore® Colon
Brochure

#brochure | Dec. 2019

Brochure Immunoscore® in Localized Colon Cancer

For Healthcare Professionals (CLIA US version)

#Immunoscore® Colon
Brochure

#brochure | Dec. 2019

Brochure Immunoscore® in Localized Colon Cancer

For Healthcare Professionals (CE/IVD version)

#Immunoscore® Colon
Video

#video | Sep. 2019

Webinar Immunoscore®: IDEA France study results in Stage III Colon Cancer - Sept. 19, 2019 | Franck Pagès, Eric Van Cutsem
#Immunoscore® Colon
Publication

#publication | Aug. 2019

Angell HK, Bruni D, Barrett JC et al.

The Immunoscore: Colon Cancer and Beyond.

Clin Cancer Res.

#Immunoscore® Colon
Poster

#poster | Jul. 2019

Poster presented at ESMO GI 2019

Significant differences in outcome between Immunoscore categories in stage I colon cancer patients

#Immunoscore® Colon
Video

#video | Jun. 2019

Extract of an interview by Cancer.fr of Professor Thierry André, on Immunoscore® in the IDEA France study (in French)
#Immunoscore® Colon
Video

#video | Jun. 2019

Jérôme Galon, winner for the European Inventor Award 2019 for Immunoscore®
#Immunoscore® Colon
Poster

#poster | Jun. 2019

Poster presented at ASCO 2019

Validation of the Immunoscore Prognostic Value in Stage III Colon Cancer Patients treated with Oxaliplatin in the prospective IDEA France cohort study (PRODIGE-GERCOR).

#Immunoscore® Colon
Publication

#publication | May. 2019

Pages F, Andre T, Taieb J et al.

Validation of the Immunoscore prognostic value in stage III colon cancer patients treated with oxaliplatin in the prospective IDEA France cohort study (PRODIGE-GERCOR)

Journal of Clinical Oncology

#Immunoscore® Colon
Video

#video | Apr. 2019

Dr. Fakih Discusses the Utility of Immunoscore® in CRC
#Immunoscore® Colon
Video

#video | Mar. 2019

Immunoscore® Webinar New data in Stage II Colon Cancer - March 21, 2019 | Jêrome Galon, PhD
#Immunoscore® Colon
Publication

#publication | Mar. 2019

Zeitoun G, Sissy CE, Kirilovsky A et al.

The Immunoscore in the Clinical Practice of Patients with Colon and Rectal Cancers.

Chirurgia (Bucur).

#Immunoscore® Colon
Video

#video | Jan. 2019

Discover how Immunoscore® is predicting the risk of relapse in localized colon cancer in a short video
#Immunoscore® Colon
Poster

#poster | Jan. 2019

Poster presented at Gastrointestinal Cancers Symposium 2019

Immunoscore clinical utility to identify good prognostic Colon Cancer Stage II patients with high-risk clinico-pathological features for whom adjuvant treatment may be avoided

#Immunoscore® Colon
Poster

#poster | Dec. 2018

Poster presented at ESMO ASIA 2018

UCGI 34 - PROSCORE: A prospective study assessing whether Immunoscore® test impacts the choice of adjuvant chemotherapy, in a multidisciplinary meeting, for treating non-metastatic colon cancer patients after curative-intent surgery

#Immunoscore® Colon
Poster

#poster | Dec. 2018

Poster presented at ESMO IO 2018

MSI status plus Immunoscore to select metastatic colorectal cancer patients for immunotherapies

#Immunoscore® Colon
Poster

#poster | Nov. 2018

Poster presented at ESMO ASIA 2018

Immunoscore feasibility study in routine postsurgical pathologic review for early‐stage colon cancer (CC) cases risk‐assessment

#Immunoscore® Colon
Publication

#publication | Oct. 2018

Angelova M, Mlecnik B, Vasaturo A et al.

Evolution of Metastases in Space and Time under Immune Selection.

Cell

#Immunoscore® Colon
Video

#video | Aug. 2018

Webinar on “Clinical utility of Immunoscore® in colon cancer” with Marc Van Den Eynde, MD, PhD | October 17, 2017
#Immunoscore® Colon
Video

#video | Aug. 2018

Dr Jerome Galon on the Prognostic Value of Immunoscore, Onclive - ASCO 2016
#Immunoscore® Colon
Video

#video | Aug. 2018

Immunoscore® Colon Symposium - June 1, 2018, Chicago | Discussion on clinical cases
#Immunoscore® Colon
Video

#video | Aug. 2018

Immunoscore® Colon Symposium - June 1, 2018, Chicago | Jérôme Galon, PhD
#Immunoscore® Colon
Video

#video | Aug. 2018

Immunoscore® Colon Symposium - June 1, 2018, Chicago | Stanley Hamilton, MD
#Immunoscore® Colon
Publication

#publication | May. 2018

Pagès F, Mlecnik B, Marliot F et al.

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study.

Lancet

#Immunoscore® Lung
Poster

#poster | Apr. 2018

Poster presented at AACR 2018

Multi-centric PD-L1 and CD8 IHC assessment in NSCLC using IMMUNOSCORE® IC previously Halioseek®) CE-IVD assay

#Immunoscore® Colon
Poster

#poster | Feb. 2018

Poster presented at ASCO GI 2018

Immunoscore provides prognostic information in low (T3N1) and high (T4 or N2) risk subsets of stage III colon carcinoma patients treated with adjuvant FOLFOX in a phase III trial [NCCTG N0147 (Alliance)

#Immunoscore® Colon
Publication

#publication | Feb. 2018

Sinicrope F, Shi Q, Hermitte F et al.

Immunoscore to provide prognostic information in low- (T1-3N1) and high-risk (T4 or N2) subsets of stage III colon carcinoma patients treated with adjuvant FOLFOX in a phase III trial (NCCTG N0147; Alliance).

J Clin Oncol.

#Immunoscore® Colon
Publication

#publication | Jan. 2018

Mlecnik B, Van den Eynde M, Bindea G et al.

Comprehensive Intrametastatic Immune Quantification and Major Impact of Immunoscore on Survival.

J Natl Cancer Inst.

#Immunoscore® Lung
Poster

#poster | Nov. 2017

Poster presented at SITC 2017

Immunoscore IC (previously Halioseek® PD‐L1/CD8), a dual CD8 and PD‐L1 IVD assay to improve NSCLC patients stratification

#Immunoscore® Colon
Poster

#poster | Jun. 2017

Poster presented at ASCO 2017

Prognostic utility of immune markers and validation of Immunoscore® in stage III colon carcinoma patients treated with adjuvant FOLFOX in a phase III trial [NCCTG N0147 (Alliance)]

#Immunoscore® Colon
Publication

#publication | May. 2017

Sinicrope F, Shi Q, Hermitte F et al.

Association of immune markers and Immunoscore with survival of stage III colon carcinoma (CC) patients (pts) treated with adjuvant FOLFOX: NCCTG N0147 (Alliance).

J Clin Oncol.

#Immunoscore® Colon
Publication

#publication | May. 2017

Galon J, Mlecnik B, Marliot F et al.

Validation of the Immunoscore (IM) as a prognostic marker in stage I/II/III colon cancer: Results of a worldwide consortium-based analysis of 1,336 patients.

J Clin Oncol.

#Immunoscore® Lung
Poster

#poster | Apr. 2017

Poster presented at AACR 2017

A new standardized CD8 and PD-L1 dual assay

#Immunoscore® Colon
Poster

#poster | Nov. 2016

Poster presented at SITC 2016

Immunoscore® analytical performance

#Immunoscore® Colon
Publication

#publication | Sep. 2016

Hermitte F

Biomarkers immune monitoring technology primer: Immunoscore® Colon.

Journal for ImmunoTherapy of Cancer

#Immunoscore® Colon
Publication

#publication | Aug. 2016

Kirilovsky A, Marliot F, El Sissy C et al.

Rational bases for the use of the Immunoscore in routine clinical settings as a prognostic and predictive biomarker in cancer patients.

Int Immunol.

#Immunoscore® Colon
Publication

#publication | Mar. 2016

Mlecnik B, Bindea G, Angell HK et al.

Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability.

Immunity

#Immunoscore® Colon
Publication

#publication | Feb. 2016

Mlecnik B, Bindea G, Kirilovsky A et al.

The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis.

Sci Transl Med.

#Immunoscore® Colon
Publication

#publication | Feb. 2011

Mlecnik B, Tosolini M, Kirilovsky A et al.

Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction.

Journal of Clinical Oncology

#Immunoscore® Colon
Publication

#publication | Sep. 2006

Galon J, Costes A, Sanchez-Cabo F et al.

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome.

Science

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