Data analysis & interpretation IMMUNOGRAM multimodal analysis and ATLAS multimarker database

Data analysis & interpretation

Our expertise in immuno-oncology and image analysis with several available and proprietary solutions (Digital Pathology) and our team of scientists and data analysts, guarantee comprehensive data analysis reports and interpretation with both of our unique platforms : Immunogram multimodal analysis and Atlas multimarker database.

 

Immunogram is a clinical research platform allowing multimodal analysis to understand the tumor microenvironment.

It integrates Immunoscore® assays, innovative technologies such as Multiplex Spatial Tissue Analysis (Brightplex®) and molecular testing in order to improve prediction of the response to therapy and personalize treatment.

Immunogram is a customizable tool enabling to picture the relevant biomarkers and phenotypes and provide a 360° view on the tumor immune contexture.

It can include several of our assays:

  • Immunoscore®  for T cells, T cells exhaustion and suppressor cells
  • Immunosign®
  • Tumor Mutational Burden
  • T cell Receptor diversity
  • MSI
  • Key Drivers Mutations
  • Integration / normalization of the biomarker landscape

All assays are amenable to clinical trial assays and companion diagnostics.

IMMUNOGRAM multimodal analysis

The Cancer Immune Atlas is a customized multimarker database in a given cancer type applying the Immunogram multimodal approach on a large number of patients’ samples.

This unique compendium of biomarkers and phenotypes provides a statistically relevant insight into the immune contexture in order to guide drug development.

Key features:

  • Immunogram - based
  • Build a compendium of phenotypic and molecular data for a given indication
  • Enable educated decisions for portfolio management, indication extension, and combination trial design
  • Sample/clinical data/ patients selected according to your objectives.
  • Easy customization to include your biomarker of interest.

ATLAS multimarker database



Resources on Immunogram


#Immunogram
Video

#video | Aug. 2020

2’ to learn more Series: Jacques Fieschi PhD, VP, R&D, presents the R&D department and its technologies, with a focus on Brightplex®
#Immunogram
Video

#video | May. 2020

Webinar: Capturing the Complexity of the Tumor Microenvironment | Jérôme Galon, PhD & Jacques Fieschi, PhD
#Immunogram
Poster

#poster | Dec. 2019

Poster presented at SITC 2019

Immunogram to decipher PD1/L1 ICI resistance: a proof of concept in advanced Non-small cell lung cancer patients of the PIONeeR Project.

#Immunogram
Video

#video | Nov. 2019

Webinar: Evaluating Biomarkers During Clinical Trials for Immunotherapies. A Case Study on the Pioneer Project
#Immunogram
Poster

#poster | Nov. 2019

Poster presented at SITC 2019

Unveilling tumor-associated macrophages (TAMs) heterogeneity and plasticity by a fully automated sequential chromogenic multiplex assay.

#Immunogram
Poster

#poster | Nov. 2019

Poster presented at SITC 2019

Cancer Immunogram: combining multi-parameter approach and machine learning to capture the complexity of tumor immune contexture.

#Immunogram
Video

#video | Sep. 2019

Webinar Biomarker Evaluation for CAR T-Cell Therapy: Impact on Drug Development
#Immunogram
Video

#video | Apr. 2019

Immunogram Clinical Seminar (Atlanta, April 2019) | Jérôme Galon, PhD
#Immunogram
Video

#video | Apr. 2019

Immunogram Clinical Seminar (Atlanta, April 2019) | Jacques Fieschi, PhD
#Immunogram
Poster

#poster | Apr. 2019

Poster presented at AACR 2019

Combining multimodal biomarkers as an immunogram to guide immunotherapy use: A Proof of Concept

#Immunogram
Brochure

#brochure | Mar. 2019

Brochure Clinical Research

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