VIDEOS & PUBLICATIONS IMPROVING LIVES

Opening up new fields of medical science

Selected videos on HalioDx

Discover HalioDx - Reportage by Grand Luminy Technopole - April 2017
Immunoscore® Webinar - March 21, 2019 | Jêrome Galon, PhD
Prof. Fakih Discusses the Utility of Immunoscore in CRC

Marwan Fakih, MD, professor, Department of Medical Oncology and Therapeutics Research, associate director for Clinical Investigations, Comprehensive Cancer Center, medical director, Judy and Bernard Briskin Center for Clinical Research, co-director, Gastrointestinal Cancer Program, and section head, Gastrointestinal Medical Oncology, City of Hope, discusses the clinical utility of the Immunoscore in patients with colorectal cancer (CRC) at the 2019 Gastrointestinal Cancers Symposium

Immunoscore® Symposium - June 1, 2018, Chicago | Stanley Hamilton, MD
Immunoscore® Symposium - June 1, 2018, Chicago | Jêrome Galon, PhD
Immunoscore® Symposium - June 1, 2018 Discussion on clinical cases with David Malka, MD, PhD & Marc Van Den Eynde, MD, PhD
Dr Jerome Galon on the Prognostic Value of Immunoscore, Onclive - ASCO 2016
Webinar on “Clinical utility of Immunoscore® in colon cancer” with Marc Van Den Eynde, MD, PhD | October 17, 2017
Webinar on Immunoscore® presented by Dr Jérôme Galon - July 2016
Webinar on Immunoscore® analytical performance presented by Fabienne Hermitte | Nov 2016
Dr Jérôme GALON, Cordeliers Research Center - EUROBIOMED & MARSEILLE IMMUNOPOLE Event - Dec. 2015
Replay of the webinar on "Halioseek® PD-L1/CD8" beyond a simple PD-L1 testing. Performance and capacity to improve NSCLC patient stratification for Immune Checkpoint Inhibitors (ICI) treatments.

Main Publications

Galon J & Bruni D

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

Nat Rev Drug Discov. 2019

18(3):197-218

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Angelova et al

Evolution of metastases in space and time under immune selection.

Cell 2018 ;

10.1016/j.cell.2018.09.018

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Pagès F et al.

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

The Lancet, 2018

May 10, 2018

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Mlecnik B et al.

Comprehensive Intrametastatic Immune Quantification and Major Impact of Immunoscore on Survival.

J Natl Cancer Inst. 2018.

Jan 1;110(1).

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Fridman WH et al.

The immune contexture in cancer prognosis and treatment.

Nat Rev Clin Oncol. 2017

Jul 25. 2017.101.

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Hermitte F

Biomarkers immune monitoring technology primer: Immunoscore® Colon

Journal for ImmunoTherapy of Cancer 2016

DOI: 10.1186/s40425-016-0161-x

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Galon J et al.

Validation of the Immunoscore (IM) as a prognostic marker in stage I/II/III colon cancer: Results of a worldwide consortium-based analysis of 1,336 patients.

2016 ASCO Annual Meeting

J Clin Oncol 34, 2016 (suppl; abstr 3500)

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Mlecnik B et al.

Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability.

Immunity. 2016 ;

Mar 15;44(3):698-711.

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Mlecnik B et al.

The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis.

Sci Transl Med. 2016 ;

24 Feb 2016, Vol. 8, Issue 327, pp. 327ra26.

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Berghoff AS et al.

Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases

OncoImmunology, 2016

Jun 9;5(1):e1057388.

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Bindea G et al.

Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

Immunity. 2013 ;

39(4):782-95.

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Galon J et al.

The continuum of cancer immunosurveillance: prognostic, predictive and mechanistic signatures.

Immunity 2013 ;

39 : 11-26.

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Fridman WH et al.

The immune contexture in human tumors: impact on clinical outcome.

Nat Rev Cancer 2012 ;

12: 298-306.

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Mlecnik B et al.

Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction.

J Clin Oncol 2011 ;

29 : 610-8.

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Pagès F et al.

In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer.

J Clin Oncol 2009 ;

27 : 5944-51.

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Galon J et al.

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome.

Science 2006 ;

313 : 1960-4.

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