Opening up new fields of medical science

Selected videos on HalioDx

Webinar Biomarker Evaluation for CAR T-Cell Therapy: Impact on Drug Development

The replay of this webinar is available here : Link

Jérôme Galon, winner for the European Inventor Award 2019 for Immunoscore®

HalioDX is part of the COLOSSUS project by performing Immunoscore and help stratification of difficult to treat mCRC patients with a final objective to Improve their management and treatment

Discover HalioDx - Reportage by Grand Luminy Technopole - April 2017

Discover videos of our Immunogram Clinical Seminar (Atlanta, April 2019)

Dr. Fakih Discusses the Utility of Immunoscore in CRC

Immunoscore® Symposium, June 2018, Chicago

Dr Jerome Galon on the Prognostic Value of Immunoscore, Onclive - ASCO 2016

Main Publications

Galon J & Bruni D

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

Nat Rev Drug Discov. 2019


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Angelova et al

Evolution of metastases in space and time under immune selection.

Cell 2018 ;


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Pagès F et al.

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

The Lancet, 2018

May 10, 2018

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Mlecnik B et al.

Comprehensive Intrametastatic Immune Quantification and Major Impact of Immunoscore on Survival.

J Natl Cancer Inst. 2018.

Jan 1;110(1).

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Fridman WH et al.

The immune contexture in cancer prognosis and treatment.

Nat Rev Clin Oncol. 2017

Jul 25. 2017.101.

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Hermitte F

Biomarkers immune monitoring technology primer: Immunoscore® Colon

Journal for ImmunoTherapy of Cancer 2016

DOI: 10.1186/s40425-016-0161-x

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Galon J et al.

Validation of the Immunoscore (IM) as a prognostic marker in stage I/II/III colon cancer: Results of a worldwide consortium-based analysis of 1,336 patients.

2016 ASCO Annual Meeting

J Clin Oncol 34, 2016 (suppl; abstr 3500)

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Mlecnik B et al.

Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability.

Immunity. 2016 ;

Mar 15;44(3):698-711.

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Mlecnik B et al.

The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis.

Sci Transl Med. 2016 ;

24 Feb 2016, Vol. 8, Issue 327, pp. 327ra26.

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Berghoff AS et al.

Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases

OncoImmunology, 2016

Jun 9;5(1):e1057388.

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Bindea G et al.

Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

Immunity. 2013 ;


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Galon J et al.

The continuum of cancer immunosurveillance: prognostic, predictive and mechanistic signatures.

Immunity 2013 ;

39 : 11-26.

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Fridman WH et al.

The immune contexture in human tumors: impact on clinical outcome.

Nat Rev Cancer 2012 ;

12: 298-306.

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Mlecnik B et al.

Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction.

J Clin Oncol 2011 ;

29 : 610-8.

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Pagès F et al.

In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer.

J Clin Oncol 2009 ;

27 : 5944-51.

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Galon J et al.

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome.

Science 2006 ;

313 : 1960-4.

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